Adiponectin (ADIPOQ) Mouse Monoclonal Antibody [Clone ID: M14-6 (A)-H11]

CAT#: AM02042PU-N

Adiponectin (ADIPOQ) mouse monoclonal antibody, clone M14-6 (A)-H11, Purified

Size: 10 ug 100 ug



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CNY 7,447.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name M14-6 (A)-H11
Applications ELISA
Recommend Dilution ELISA.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant human Adiponectin from E. coli
Specificity This antibody detects Adiponectin.
Formulation PBS pH 7,4
State: Purified
State: Lyophilized Ig fraction
Reconstitution Method Restore in aqua bidest to 1 mg/ml.
Purification Protein G chromatography
Conjugation Unconjugated
Storage Condition Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Gene Name adiponectin, C1Q and collagen domain containing
Background Adipose cells produce and secrete numerous physiologically important proteins, such as Lipoprotein Lipase, Leptin, and Adipocyte Complement Related protein of 30 kDa, also known as Acrp30 or Adiponectin. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, Adiponectin mRNA is induced >100 fold. Adiponectin improves the ability of insulin to suppress glucose production, at sub physiological levels, thereby linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol 3 kinase (PI3K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. Adiponectin mRNA is significantly reduced in adipose tissue of obese patients with Type 2 diabetes. The structural similarity of Adiponectin to TNF alpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Adiponectin is implicated as a regulator of whole body energy homeostasis.
Synonyms ADIPOQ, ACDC, ACRP30, APM1, GBP28
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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