Stefin B (CSTB) (1-98) Mouse Monoclonal Antibody [Clone ID: 2F1]

Specifications

Product Data
Clone Name	2F1
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: 1:1000 ~ 1:3,000; starting diluton 1:1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CSTB (1-98aa) purified from E. coli
Specificity	This antibody detetcts CSTB.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cystatin B
Database Link	Entrez Gene 1476 Human UniProt ID P04080
Background	CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to from a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes in cells. CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.
Synonyms	Stefin-B, CPI-B, CSTB, CST6, STFB
Reference Data

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