TSH beta (TSHB) Mouse Monoclonal Antibody [Clone ID: 204-12410]

Specifications

Product Data
Clone Name	204-12410
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human pituitary gland.
Specificity	This antibody reacts to Thyroid Stimulating Hormone (TSH), beta subunit. Cross-reactivity: FSH: 0.7% LH: 0.5% TSH alpha: 1.5%
Formulation	10mM Phosphate, pH 7.4 containing 150mM Sodium chloride and 0,09% Sodium Azide as preservative. State: Purified State: Liquid (sterile filtered) purified fraction (>90% pure by SDS-PAGE).
Concentration	lot specific
Purification	Protein A Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one week or (in aliquots) at -40°C for longer. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freezing and thawing.
Gene Name	thyroid stimulating hormone beta
Database Link	Entrez Gene 7252 Human UniProt ID P01222
Background	Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
Synonyms	Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta
Reference Data

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