IL1 alpha (IL1A) Mouse Monoclonal Antibody [Clone ID: 1F3B3]

Specifications

Product Data
Clone Name	1F3B3
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000.  Western Blot: 1/500-1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human IL1a expressed in E. Coli.
Specificity	Recognizes Human Interleukin-1 alpha / IL-1A. Other species not tested.
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interleukin 1 alpha
Database Link	Entrez Gene 3552 Human UniProt ID P01583
Background	Interleukin-1 alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Synonyms	IL-1 alpha, IL1F1, IL1A, Hematopoietin-1
Reference Data

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