AKT2 Mouse Monoclonal Antibody [Clone ID: 1B6]

Specifications

Product Data
Clone Name	1B6
Applications	ELISA, IF, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human, Monkey, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human AKT2 expressed in E. Coli.
Specificity	This antibody reacts to AKT2.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	60 kDa
Gene Name	AKT serine/threonine kinase 2
Database Link	Entrez Gene 208 Human UniProt ID P31751
Background	Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.
Synonyms	RAC-PK-beta, Protein kinase Akt-2, Protein kinase B beta
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.