COX4 (COX4I1) Mouse Monoclonal Antibody [Clone ID: 6B3]

Specifications

Product Data
Clone Name	6B3
Applications	ELISA, FC, IF, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400.
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human COX4I1 expressed in E. Coli.
Specificity	Recognizes  COX IV isoform 1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	19 kDa
Gene Name	cytochrome c oxidase subunit 4I1
Database Link	Entrez Gene 1327 Human UniProt ID P13073
Background	Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.
Synonyms	Cytochrome c oxidase polypeptide IV, COX IV-1, COX4I1, COX4
Reference Data

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