ELK1 pSer383 Mouse Monoclonal Antibody [Clone ID: D7H2]

CAT#: AM09316PU-N

ELK1 pSer383 mouse monoclonal antibody, clone D7H2, Aff - Purified



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CNY 7,733.00


货期*
4周

规格
    • 500 ug

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Specifications

Product Data
Clone Name D7H2
Applications ELISA
Recommend Dilution Indirect ELISA: the antibody is reactive to the un-conjugated Serine383 phosphorylated human ELK-1 peptide, and reactive to the serine383 phosphorylated human ELK-1 peptide conjugated with KLH or the peptide-BSA conjugate.
The suggested antigen Coating quantity is 1 µg/ml of peptide/or peptide conjugating in pH 9.5 carbonate buffer, 100 µl/well.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Peptide of a phosphorylated fragment of ELK1 (pSer383) conjugated with KLH.
Specificity Reactive to the un-conjugated serine383 phosphorylated Human ELK-1 peptide fragment, and reactive to the Serine383 phosphorylated Human ELK-1 peptide fragment conjugated to KLH or the peptide- BSA conjugate. Not reactive to KLH or BSA.
Formulation 0.01M PBS, pH 7.0 without preservatives
State: Aff - Purified
State: Lyophilized purified IgG fraction
Reconstitution Method Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Upon receipt, store (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name ELK1, ETS transcription factor
Background ELK1 belongs to the EST transcription factor family. Proteins in the family have a unique DNA binding domain that binds to conserved DNA sequences. Phosphorylation of ELK1 at serine 383 and 389 by mitogen-activated protein kinases (MAPKs) activates ELK1. The binding of ELK1 to target sequences is also regulated by its co-factor, serum response factor (SRF), by alternative splicing, and by SUMOylation. ELK1 regulates the transcription of c-fos and genes encoding cytoskeleton proteins, and was found to play a role in longterm memory formation, drug addiction and other neurological disorders.
Synonyms Elk-1
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Endometrial cancer, ErbB signaling pathway, Focal adhesion, GnRH signaling pathway, Insulin signaling pathway, MAPK signaling pathway, Prion diseases
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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