Cytokeratin 18 (KRT18) (79-430) Mouse Monoclonal Antibody [Clone ID: AT2G3]

Specifications

Product Data
Clone Name	AT2G3
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/250-1/1000.  Immunofluorescence: 1/250-1/1000.  Immunohistochemistry on Paraffin Embedded Tissues: 1/50.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human KRT18 (79-430 aa) purified from E. coli
Specificity	The antibody recognizes Human KRT18. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	keratin 18
Database Link	Entrez Gene 3875 Human UniProt ID P05783
Background	Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers. Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases.
Synonyms	Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18
Reference Data
Protein Pathways	Pathogenic Escherichia coli infection

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