SRC Mouse Monoclonal Antibody [Clone ID: 17AT28]

Specifications

Product Data
Clone Name	17AT28
Applications	IHC, IP, WB
Recommend Dilution	ELISA: 1/1,000 Western blotting: 1/100-1/500 Immunohistochemistry: 1/50-1/100 Immunoprecipitation: 2 ug/test.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody is generated from mouse immunized with a recombinant protein of full length human SRC.
Specificity	This antibody is specific to Src.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	SRC proto-oncogene, non-receptor tyrosine kinase
Database Link	Entrez Gene 6714 Human UniProt ID P12931
Background	The gene for SRC is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC, the protein encoded by this gene, is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in SRC could be involved in the malignant progression of colon cancer.
Synonyms	c-Src, pp60c-src
Reference Data

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