CD7 Mouse Monoclonal Antibody [Clone ID: 142.9]

Specifications

Product Data
Clone Name	142.9
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on frozen sections: 1 µg/ml (1:200). Has been described to work in FACS. Suggested positive control: Human tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human T cells
Specificity	This antibodyrecognizes CD7, a 40kD cell surface glycoprotein.
Formulation	Stock solution contains 0.2mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative. State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	Reconstitute by adding 0.5ml distilled water.
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD7 molecule
Database Link	Entrez Gene 924 Human UniProt ID P09564
Background	CD7 is one of the earliest differentiation markers expressed by immature T cells and is also expressed by mature T cells and NK cells, and is a clinical marker for T cell acute lymphocytiyc leukemia (ALL).
Synonyms	GP40, TP41, Leu-9
Note	Functional studies have shown that CD7 monoclonal antibodies can directly activate γδ-positive T cells. Antigen distribution: Isolated cells: The antibody stains approximately 50-90% of human peripheral blood mononuclear cells.
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Hematopoietic cell lineage

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