IL9R Mouse Monoclonal Antibody [Clone ID: AH9R7]

Specifications

Product Data
Clone Name	AH9R7
Applications	ELISA, FC, FN
Recommend Dilution	Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CD129-transfected cell line
Specificity	This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
Formulation	Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	interleukin 9 receptor
Database Link	Entrez Gene 3581 Human UniProt ID Q01113
Background	CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
Synonyms	Interleukin-9 receptor, IL-9R, IL-9 receptor
Reference Data

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