TSG101 (201-281) Mouse Monoclonal Antibody [Clone ID: 5B7]

Specifications

Product Data
Clone Name	5B7
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Immunofluorescence: 10 µg/ml. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/500 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	TSG101 (NP_006283, 201 a.a. ~ 281 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity	This antibody reacts to TSG101.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tumor susceptibility 101
Database Link	Entrez Gene 7251 Human UniProt ID Q99816
Background	The tumor susceptibility gene 101 (TSG101) was first discovered in a screen for potential tumor suppressors. Altered transcripts of this gene have been detected in sporadic breast carcinomas and other malignancies. In mice the gene has been shown to be essential for growth, proliferation and survival of mammary epithelial cells. TSG101 is also a component of the ESCRt-1 complex, a regulator of the vesicular trafficking process. In addition it is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies and is involved the budding of many viruses.
Synonyms	TSG10; VPS23
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Endocytosis

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.