c-Myc (MYC) Mouse Monoclonal Antibody [Clone ID: CT14.G4]

CAT#: AM33356PU-S

c-Myc (MYC) mouse monoclonal antibody, clone CT14.G4, Purified

Size: 20 ug 100 ug



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CNY 5,606.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name CT14.G4
Applications FC, IF, IHC, IP, WB
Recommend Dilution ELISA: Use BSA free Antibody for coating.
Flow Cytometry: 0.5-1 μg/million cells.
Immunofluorescence: 1-2 μg/ml.
Western Blotting: 0.5-1 μg/ml.
Immunoprecipitation: 1-2 μg/500 μg protein lysate.
Immunohistochemistry on Frozen Sections: 0.5-1.0 μg/ml for 30 minutes at RT.
Positive Control: HL-60 cells or breast carcinoma.
Reactivity Chimpanzee, Human, Gorilla
Host Mouse
Clonality Monoclonal
Immunogen A synthetic peptide, corresponding to aa 408-439 from C-terminus of Human c-myc, coupled to KLH.
Specificity Recognizes c-Myc Oncoprotein.
Cellular Localization: Nuclear.
Formulation 10mM PBS
State: Purified
State: Liquid purified IgG fraction from Bioreactor Concentrate
Stabilizer: 0.05% BSA
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein A/G Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
Predicted Protein Size 62-64 kDa
Gene Name v-myc avian myelocytomatosis viral oncogene homolog
Background The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Synonyms Transcription factor p64, BHLHE39
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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