GCLM Mouse Monoclonal Antibody [Clone ID: AT2D12]

CAT#: AM50016PU-N

GCLM mouse monoclonal antibody, clone AT2D12, Purified

Size: 50 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

CNY 6,620.00


货期*
5周

规格
    • 100 ul

Product images

Specifications

Product Data
Clone Name AT2D12
Applications ELISA, FC, IF, WB
Recommend Dilution ELISA.
Western blot: 1/3000 (using HeLa cells (40 µg), resolved by SDS-PAGE).
Flow cytometry: 2-5 µg in 1x106 cells (in HeLa cell line).
Immunofluorescence/Immnunocytochemistry: 1/100 (in HeLa cell line).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant human GCLM (1-274aa) purified from E. coli
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name glutamate-cysteine ligase modifier subunit
Background GCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer.
Synonyms Gamma-ECS regulatory subunit, GCS light chain
Reference Data
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...