ACAT1 Mouse Monoclonal Antibody [Clone ID: AT15E5]

CAT#: AM50027PU-N

ACAT1 mouse monoclonal antibody, clone AT15E5, Purified

Size: 50 ul 100 ul



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CNY 6,620.00


货期*
5周

规格
    • 100 ul

Cited in 1 publication.

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Specifications

Product Data
Clone Name AT15E5
Applications ELISA, WB
Recommend Dilution The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1/1000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human ACAT1 (34-427aa) purified from E. coli
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name acetyl-CoA acetyltransferase 1
Background ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded.
Synonyms ACAT; MAT; T2; THIL
Reference Data
Protein Families Druggable Genome
Protein Pathways Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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