PGAM1 Mouse Monoclonal Antibody [Clone ID: AT1G4]

Specifications

Product Data
Clone Name	AT1G4
Applications	ELISA, FC, IF, WB
Recommend Dilution	The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PGAM1 (1-254aa) purified from E. coli.
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphoglycerate mutase 1
Database Link	Entrez Gene 5223 Human UniProt ID P18669
Background	PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this protein cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.
Synonyms	PGAM 1, Phosphoglycerate mutase 1, PGAMA, PGAM-B
Reference Data
Protein Pathways	Glycolysis / Gluconeogenesis, Metabolic pathways

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