Oxytocin Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, R, WB
Recommend Dilution	RIA: 1/80,000 (Ref.1-5). Western blot. Immunohistochemistry on Paraffin Sections: 1/500 (Ref.5).
Reactivity	Bovine, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Oxytocin Bovine Thyroglobulin conjugated
Specificity	This antibody detects Human, Bovine and others species Oxytocin. No cross reaction with Lys-/Arg-Vasopressin, Neurophysin, or pituitary hormones (e.g. Prolactin).
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Database Link	UniProt ID P69043
Background	There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Synonyms	OXT, Ocytocin
Reference Data

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