Herpes Virus Type 8 / HHV8 Cyclin Sheep Polyclonal Antibody

Specifications

Product Data
Applications	IP, WB
Recommend Dilution	Immunoblotting: 1-5 µg/ml. Immunoprecipitation: 10-20 µg/ml.
Reactivity	Human
Host	Sheep
Clonality	Polyclonal
Immunogen	Inclusion Bodies from E. Coli expressing His-tagged full length Human Cyclin G2 protein.
Specificity	This antibody recognizes Human Herpes Virus 8 cyclin (HHV8 cyclin). Other species not tested.
Formulation	PBS State: Purified State: Liquid (0.2µm sterile filtered) purified IgG fraction Preservative: 0.08% Sodium Azide
Purification	Ammonium Sulfate Precipitation
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Predicted Protein Size	28.1 kDa
Background	Human herpervirus-8 (HHV-8) cyclin is a component of the HHV-8 virus particle. HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.
Synonyms	HHV-8, KHSV
Reference Data

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