BAX Rabbit Polyclonal Antibody

CAT#: AP06027PU-S

BAX rabbit polyclonal antibody, Aff - Purified

Size: 100 ug 25 ul



Need it in bulk or conjugated?
Get a free quote

CNY 800.00


货期*
2周

规格
    • 25 ul

Product images

Specifications

Product Data
Applications IHC, IP, WB
Recommend Dilution Western blot: 1/500-1/1000.
Immunohistochemistry on Paraffin sections: 1/50-1/200.
Immunoprecipitation: 1/50-1/200.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to the N-terminus of Human Bax.
Specificity This antibody detects endogenous levels of Bax-α/β/δ/ε/σ protein (region surrounding Ser4).
Formulation Phosphate buffered saline (PBS), pH 7.2
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% Sodium azide
Concentration 1.0 mg/ml
Purification Affinity chromatography using epitope-specific immunogen (> 95% oure by SDS-PAGE)
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Predicted Protein Size ~21 kDa
Gene Name BCL2 associated X protein
Background The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax p21 (for Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Synonyms Apoptosis regulator BAX, BCL2L4, Bcl2-L-4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...