PRDM1 (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/2000 (Detection Limit). Western blot: 1-3 µg/ml. Approx 100kDa band observed in Human Brain (cerebellum) lysates (calculated MW of 91.8kDa according to NP_001189.2 and of 76.8 according to NP_878911.1).
Reactivity	Bovine, Canine, Human, Mouse, Porcine, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-KVKQETVEPMDP, from the C-Terminus of the protein sequence according to NP_001189.2; NP_878911.1.
Specificity	This antibody is expected to recognize both reported isoforms (NP_001189.2 and NP_878911.1).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	PR domain 1
Database Link	Entrez Gene 12142 MouseEntrez Gene 309871 RatEntrez Gene 639 Human UniProt ID O75626
Background	PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction.
Synonyms	BLIMP-1, PRDI-BF1, PRDI-binding factor 1
Reference Data
Protein Families	Transcription Factors

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