HSP90AA1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 1/1000.
Reactivity	Human, Mouse, Rabbit, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant human Hsp90 R protein
Specificity	This antibody reacts to Heat Shock Protein 90 (HSP90).
Formulation	PBS containing 0.09% azide, 50% glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	heat shock protein 90kDa alpha family class A member 1
Database Link	Entrez Gene 15519 MouseEntrez Gene 299331 RatEntrez Gene 3320 Human UniProt ID P07900
Background	Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation. It also stabilizes a number of proteins required for tumor growth, which is why Hsp90 inhibitors are investigated as anti-cancer drugs. Heat shock proteins, as a class, are among the most highly expressed cellular proteins across all species.
Synonyms	HSP90AB1, HSP90B, HSPC2, HSPCB, HSP84, HSP-90, HSP-84, Heat shock protein HSP 90-beta, HSP84, HSP-84, HSP90AA1, HSP90A, HSPC1, HSPCA, HSP86, HSP-86, Renal carcinoma antigen NY-REN-38, Heat shock protein HSP 90-alpha, HSP86, HSP-86
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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