KRT6A Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/100-1/200 (after microwave treatment).  Positive Control: Human psoriatic skin; rete ridges of foot sole Incubation Time: 1 h at RT.
Reactivity	Human, Mouse
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic peptide of Human keratin K6 (C-SSTIKYTTTSS), coupled to KLH
Specificity	This antibody reacts with  Human type II (basic) Keratin K6 (formerly also designated Cytokeratin 6); MW 56,000 (pI 7.8).  In immunohistochemistry, the antibody detects Keratin K6 in non-keratinized squamous epithelia, follicular outer root sheath and proliferating cells of epidermis (e.g. within psoriatic lesions). It is completely negative on non-stratified epithelia. Suitable for discrimination of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma.
Formulation	State: Serum State: Liquid Stabilized Antiserum with 0.09% Sodium Azide and 0.5% BSA
Conjugation	Unconjugated
Storage Condition
Gene Name	keratin 6A
Database Link	Entrez Gene 3853 Human UniProt ID P02538
Synonyms	Cytokeratin 6, KRT-6, K6, KRT6A, KRT6D, KRT6B, KRT6C, KRT6E, KRTL1
Reference Data

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