Ataxin 3 (ATXN3) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow cytometric: 1/10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 267~297 amino acids from the Center region of human ATXN3
Specificity	This antibody reacts to Ataxin-3.
Formulation	PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ataxin 3
Database Link	Entrez Gene 4287 Human UniProt ID P54252
Background	ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.
Synonyms	ATXN3, ATX3, MJD, MJD1, SCA3
Note	Molecular Weight: 41781 Da
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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