Artemis (DCLRE1C) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 28~58 amino acids from the N-terminal region of Human DCLRE1C.
Specificity	This antibody recognizes Human Artemis (N-term).
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	DNA cross-link repair 1C
Database Link	Entrez Gene 227525 MouseEntrez Gene 64421 Human UniProt ID Q96SD1
Background	DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide.
Synonyms	DCLRE1C, ASCID, SCIDA, SNM1C, SNM1-like protein, A-SCID protein
Note	Molecular Weight: 78436 Da
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle, Non-homologous end-joining, Primary immunodeficiency

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