Collagen IV (COL4A3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/500-1/2000.  Immunofluorescence.  Immunohistochemistry: 1/50-1/500.
Reactivity	Human, Rat, Zebrafish
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from C-term domain of Human COL4A3
Specificity	This antibody reacts with Human fragment (26 kDa) and precursor (161 kDa) of COL4A3 protein.  Cross reacts with Mouse, Rat, Zebrafish and other species.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Serum State: Lyophilized Serum Preservative: None
Reconstitution Method	Restore in 200 µl of distilled water.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	collagen type IV alpha 3 chain
Database Link	Entrez Gene 1285 Human UniProt ID Q01955
Background	COL4A3 (Collagen, type IV, alpha 3) belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. Type IV collagen is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity.
Synonyms	COL4A3
Reference Data

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