Alkaline Phosphatase (ALPL) Mouse Monoclonal Antibody [Clone ID: BGN/03/661]

Specifications

Product Data
Clone Name	BGN/03/661
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: In Immunoblotting this antibody stains a band of BAP at around 70 kDa.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Alkaline Phosphatase prepared from Human bone.
Specificity	The antibody clone BGN/03/661 is specific for Alkaline Phosphatase. It detects the tissue specific isotypes, BAP, PLAP, and IAP (Bone, Placental and Intestinal AP), but may react with other Alkaline Phosphatases.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	alkaline phosphatase, liver/bone/kidney
Database Link	Entrez Gene 249 Human UniProt ID P05186
Background	Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
Synonyms	AP-TNAP, TNSALP
Reference Data

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