CoREST (RCOR1) Mouse Monoclonal Antibody [Clone ID: OTI9F6]

Specifications

Product Data
Clone Name	OTI9F6
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 256-485 of human RCOR1 (NP_055971) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	REST corepressor 1
Database Link	NP_055971 Entrez Gene 217864 MouseEntrez Gene 102554884 RatEntrez Gene 23186 Human UniProt ID Q9UKL0
Background	This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]
Synonyms	COREST; RCOR
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Huntington's disease

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