CD40 Mouse Monoclonal Antibody [Clone ID: G28-5]

Specifications

Product Data
Clone Name	G28-5
Applications	FC, FN, IHC
Recommend Dilution	Cell activation, IHC paraffin, flow cytometry.  Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml for cellular activation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	human erythrocyte-rosette-negative tonsillar lymphocyte
Specificity	human CD40
Formulation	100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8 State: Purified
Concentration	lot specific
Purification	QMA Hyper D ion exchange chromatography
Conjugation	Unconjugated
Storage Condition	-20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing.
Gene Name	CD40 molecule
Database Link	Entrez Gene 958 Human UniProt ID P25942
Background	CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the low affinity nerve growth factor (NGF) receptor and CD95/Fas. CD40 is the receptor for CD40 ligand expressed on activated CD4+ T cells. Clark E.A. et al. have reported a mAb binding to a 50 kDa B-cell surface marker (BP50) which augments B-cell activation and proliferation. This B-cell marker was CD40. (Clark E.A.. et al, 1985 ; PNAS, 82 :1766 ; Clark E.A. et al, 1986 ; PNAS, 83 : 4494-4498)
Synonyms	TNFRSF5, CDw40, Bp50
Reference Data

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