TRPM8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:10~50
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This TRPM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-552 amino acids from the Central region of human TRPM8.
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	127685 Da
Gene Name	transient receptor potential cation channel subfamily M member 8
Database Link	NP_076985 Entrez Gene 79054 Human UniProt ID Q7Z2W7
Background	TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Synonyms	LTRPC6; TRPP8
Reference Data
Protein Families	Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

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