IL17 (IL17A) Mouse Monoclonal Antibody [Clone ID: 4H1524.1]
CAT#: TA319544
Mouse monoclonal Anti-Human IL-17A (MOUSE) Biotin Conjugated antibody
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CNY 8,363.00
货期*
5周
规格
经常一起买 (4)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | 4H1524.1 |
Applications | WB |
Recommend Dilution | WB: 1ug/mL, FC: User Optimized |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Biotin |
Storage Condition | Store at -20°C as received. |
Gene Name | interleukin 17A |
Database Link | |
Synonyms | CTLA8; IL-17; IL-17A; IL17 |
Note | IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in Immunology research. |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction |
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