ROCK2 Rabbit Polyclonal Antibody

CAT#: TA322700S

Anti-ROCK2 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human Rho-associated, coiled-coil containing protein kinase 2 (ROCK2), 20 µg
    • 20 ug

CNY 2,900.00


Transient overexpression lysate of Rho-associated, coiled-coil containing protein kinase 2 (ROCK2)
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: Mouse brain tissue lysate
IHC: 50-200
Positive control: Human tonsil
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to C terminal 300 amino acids of human Rho-associated, coiled-coil containing protein kinase 2
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 161 kDa
Gene Name Rho associated coiled-coil containing protein kinase 2
Background The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis; smooth muscle contraction; the formation of actin stress fibers and focal adhesions; and the activation of the c-fos serum response element. This protein; which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction; actin cytoskeleton organization; stress fiber and focal adhesion formation; neurite retraction; cell adhesion and motility via phosphorylation of ADD1; BRCA2; CNN1; EZR; DPYSL2; EP300; MSN; MYL9/MLC2; NPM1; RDX; PPP1R12A and VIM. Phosphorylates SORL1 and IRF4.
Synonyms ROCK-II
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, TGF-beta signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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