LRPAP1 Rabbit Polyclonal Antibody

CAT#: TA323026S

Anti-LRPAP1 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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Transient overexpression lysate of low density lipoprotein receptor-related protein associated protein 1 (LRPAP1)
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: 293T cells and fetal kidney tissue
IHC: 50-200
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 344-357 amino acids of Human low density lipoprotein receptor-related protein associated protein 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 41 kDa
Gene Name LDL receptor related protein associated protein 1
Background Low density lipoprotein receptor-related protein associated protein 1?also known as?LRPAP1?or?RAP?is a chaperone?protein?which in humans is encoded by the LRPAP1?gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor; as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors; and may prevent receptor aggregation and degradation in the endoplasmic reticulum; thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin; since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.
Synonyms A2MRAP; A2RAP; alpha-2-MRAP; HBP44; MRAP; MYP23; RAP
Reference Data
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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