SPDEF Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-100 Positive control: Human colorectal cancer Predicted cell location: Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 129-332 amino acids of human SAM pointed domain containing ets transcription factor
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SAM pointed domain containing ETS transcription factor
Database Link	NP_036523 Entrez Gene 30051 MouseEntrez Gene 25803 Human UniProt ID O95238
Background	The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells; and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain; breast; lung and ovarian tumors; compared to the corresponding normal tissues; and it shows better tumor-association than other cancer-associated molecules; making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	bA375E1.3; PDEF
Reference Data
Protein Families	Transcription Factors

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