KCNK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	KCNK1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 37 kDa; Observed: 35 kDa
Gene Name	potassium two pore domain channel subfamily K member 1
Database Link	NP_002236 Entrez Gene 16525 MouseEntrez Gene 59324 RatEntrez Gene 3775 Human UniProt ID O00180
Background	The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1). Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3).
Synonyms	DPK; HOHO; K2P1; K2p1.1; KCNO1; TWIK-1; TWIK1
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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