APLP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against APL1β28. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	amyloid beta precursor like protein 1
Database Link	Entrez Gene 333 Human UniProt ID P51693
Background	APLP1 (amyloid precursor-like protein 1) is part of a conserved family of type-I transmembrane proteins, including the amyloid precursor protein (APP) and APLP2 (amyloid precursor-like protein 2) which are homologous in function. APP and APLPs have roles in neuronal differentiation, synaptogenesis, neurite outgrowth, and synaptic plasticity. Subsequent γ-cleavage of membrane-bound stubs of APLP1 generates Aβ-like peptides with 25, 27 and 28 residues. APL1β28 has been suggested to be a surrogate marker for Aβ1–42 production in the brain. This antibody was generated by immunization of rabbits with APL1β28 coupled to a carrier protein.
Synonyms	APLP; APLP-1
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.