BCL10 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4A8]

CAT#: TA501237AM

BCL10 mouse monoclonal antibody, clone 4A8, Biotinylated

Conjugation: Unconjugated Biotin HRP PE



  View other "OTI4A8" antibodies (5)

Need it in bulk or conjugated?
Get a free quote

CNY 3,990.00


货期*
2周

规格
    • 100 ul

经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Transient overexpression lysate of B-cell CLL/lymphoma 10 (BCL10)
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI4A8
Applications FC, IF, IHC, WB
Recommend Dilution WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 26.1 kDa
Gene Name BCL10 immune signaling adaptor
Background This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Synonyms c-E10; CARMEN; CIPER; CLAP; IMD37; mE10
Reference Data
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, T cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Other Versions

Customer Reviews 
Loading...