PMS2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA 1:5000-10000, WB 1:500
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is raised against a recombinant protein of PMS2 expressed in HEK293 cells
Formulation	Tissue culture buffer containing 1% BSA and 0.02% Sodium azide
Concentration	Lot dependent; please refer to CoA along with shipment
Purification	Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	95.8 kDa
Gene Name	PMS1 homolog 2, mismatch repair system component
Database Link	NP_000526 Entrez Gene 5395 Human UniProt ID P54278
Background	This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]
Synonyms	HNPCC4; MLH4; MMRCS4; PMS2CL; PMSL2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Mismatch repair

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.