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MCM6 (NM_005915) Human Tagged Lenti ORF Clone
CAT＃: RC207097L3
- LentiORF®
Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), Myc-DDK-tagged
"NM_005915" in other vectors (7)
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CNY 7,700.00
Product images
CNY 600.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | MCG40308; Mis5; P105MCM |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC207097).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_005915 |
| ORF Size | 2463 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005915.4 |
| RefSeq Size | 3791 bp |
| RefSeq ORF | 2466 bp |
| Locus ID | 4175 |
| UniProt ID | Q14566 |
| Domains | MCM |
| Protein Families | Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Cell cycle, DNA replication |
| MW | 92.9 kDa |
| Gene Summary | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. [provided by RefSeq, May 2012] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207097 | MCM6 (Myc-DDK-tagged)-Human minichromosome maintenance complex component 6 (MCM6) |
CNY 5,800.00 |
|
| RC207097L1 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC207097L2 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), mGFP tagged |
CNY 7,700.00 |
|
| RC207097L4 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), mGFP tagged |
CNY 7,700.00 |
|
| RG207097 | MCM6 (tGFP-tagged) - Human minichromosome maintenance complex component 6 (MCM6) |
CNY 6,370.00 |
|
| SC110945 | MCM6 (untagged)-Human minichromosome maintenance complex component 6 (MCM6) |
CNY 6,024.00 |
|
| SC323955 | MCM6 (untagged)-Human minichromosome maintenance complex component 6 (MCM6) |
CNY 6,024.00 |
