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Paxillin (PXN) (NM_002859) Human Untagged Clone
CAT＃: SC108478
PXN (untagged)-Human paxillin (PXN), transcript variant 2
CNY 6,232.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108478 sequence for NM_002859 edited (data generated by NextGen Sequencing)
ATGGACGACCTCGACGCCCTGCTGGCGGACTTGGAGTCTACCACCTCCCACATCTCCAAA CGGCCTGTGTTCTTGTCGGAGGAGACCCCCTACTCATACCCAACTGGAAACCACACATAC CAGGAGATTGCCGTGCCACCCCCCGTCCCCCCACCCCCGTCCAGCGAGGCCCTCAATGGC ACAATCCTTGACCCCTTAGACCAGTGGCAGCCCAGCGGCTCCCGATTCATCCACCAGCAG CCTCAGTCCTCATCACCTGTGTACGGCTCCAGTGCCAAAACTTCCAGTGTCTCCAACCCT CAGGACAGTGTTGGCTCTCCGTGCTCCCGAGTGGGTGAGGAGGAGCACGTCTACAGCTTC CCCAACAAGCAGAAATCAGCTGAGCCTTCACCCACCGTAATGAGCACGTCCCTGGGCAGC AACCTTTCTGAACTCGACCGCCTGCTGCTGGAACTGAACGCTGTACAGCATAACCCGCCA GGCTTCCCTGCAGATGAGGCCAACTCAAGCCCCCCGCTTCCTGGGGCCCTGAGCCCCCTC TATGGTGTCCCAGAGACTAACAGCCCCTTGGGAGGCAAAGCTGGGCCCCTGACGAAAGAG AAGCCTAAGCGGAATGGGGGCCGGGGCCTGGAGGACGTGCGGCCCAGTGTGGAGAGTCTC TTGGATGAACTGGAGAGCTCCGTGCCCAGCCCCGTCCCTGCCATCACTGTGAACCAGGGC GAGATGAGCAGCCCGCAGCGCGTCACCTCCACCCAACAGCAGACACGCATCTCGGCCTCC TCTGCCACCAGGGAGCTGGACGAGCTGATGGCTTCGCTGTCGGATTTCAAGTTCATGGCC CAGGGGAAGACAGGGAGCAGCTCACCCCCTGGGGGGCCCCCGAAGCCCGGGAGCCAGCTG GACAGCATGCTGGGGAGCCTGCAGTCTGACCTGAACAAGCTGGGGGTCGCCACAGTCGCC AAAGGAGTCTGCGGGGCCTGCAAGAAGCCCATCGCCGGGCAGGTTGTGACCGCCATGGGG AAGACGTGGCACCCCGAGCACTTCGTCTGCACCCACTGCCAGGAGGAGATCGGATCCCGG AACTTCTTCGAGCGGGATGGACAGCCCTACTGTGAAAAGGACTACCACAACCTCTTCTCC CCGCGCTGCTACTACTGCAACGGCCCCATCCTGGATAAAGTGGTGACAGCCCTTGACCGG ACGTGGCACCCTGAACACTTCTTCTGTGCACAGTGTGGAGCCTTCTTTGGTCCCGAAGGG TTCCACGAGAAGGACGGCAAGGCCTACTGTCGCAAGGACTACTTCGACATGTTCGCACCC AAGTGTGGCGGCTGCGCCCGGGCCATCCTGGAGAACTATATCTCAGCCCTCAACACGCTG TGGCATCCTGAGTGCTTTGTGTGCCGGGAATGCTTCACGCCATTCGTGAACGGCAGCTTC TTCGAGCACGACGGGCAGCCCTACTGTGAGGTGCACTACCACGAGCGGCGCGGCTCGCTG TGTTCTGGCTGCCAGAAGCCCATCACCGGCCGCTGCATCACCGCCATGGCCAAGAAGTTC CACCCCGAGCACTTCGTCTGTGCCTTCTGCCTCAAGCAGCTCAACAAGGGCACCTTCAAG GAGCAGAACGACAAGCCTTACTGTCAGAACTGCTTCCTCAAGCTCTTCTGCTAG Clone variation with respect to NM_002859.3 217 a=>g >OriGene 5' read for NM_002859 unedited
NAAAAAAAGAGAAAAAAACTTNNNNTNNNNNNNNNGTTTTTACCCCGCCCCTTGCCCCAA AGGGCGGTAGGCGTGTACGGTGGGAAGTCTATATAAGCAGAGCTCATTTAGGTGACACTA TAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGCTCGCGGC GGAAAAGTTGCGGGGCATAGACGAGCGGCCCCGGGACGGGCAGCTAGCGCGACCCTGAGC CGGCGCCCGTGGTCCGGCCATGGACGACCTCGACGCCCTGCTGGCGGACTTGGAGTCTAC CACCTCCCACATCTCCAAACGGCCTGTGTTCTTGTCGGAGGAGACCCCCTACTCATACCC AACTGGAAACCACACATACCAGGAGATTGCCGTGCCACCCCCCGTCCCCCCACCCCCGTC CAGCGAGGCCCTCAATGGCACAATCCTTGACCCCTTAGACCAGTGGCAGCCCAGCGGCTC CCGATTCATCCACCAGCAGCCTCAGTCCTCATCACCTGTGTACGGCTCCAGTGCCAAAAC TTCCAGTGTCTCCAACCCTCAGGACAGTGTTGGCTCTCCGTGCTCCCGAGTGGGTGAGGA GGAGCACGTCTACAGCTTCCCCAACAAGCAGAAATCAGCTGAGCCTTCACCCACCGTAAT GAGCACGTCCCTGNGCAGCAACCTTTCTGAACTCGACCGCCTGCTGCTGGAACTGAACGC TGTACAGCATAACCCGCCAGGCTTCCCTGCAGATGAGGCCAACTCAAGCCCCCCGCTTTC TGGGGCCCCTGAGCCCCCTCTATGGTGTCCCAGAGACCTACAGCCCCTTGGGNAGCAAAG CTGGCCCCCTGACGAAAGAGAAGCCTAAGCGGAATGGGGGCCGGGGCCTNGAAGNACGTG CCGCCCCATGTGGNAGAGTCTCTTGGATGAACTGAAGAGCTCGTGCCCCACCCCGTTCCT GCCT >OriGene 3' read for NM_002859 unedited
GGGGAATCAGCGTGNACAGGCCCGTTAGCGANGATCGAAAACCTTTTTTTTTTTTTGAAA ACATGGGCAAACTTTATTGGGGCATAAATCACAGGGAATTTGAAATGGGGAAAAGCCAGC TTGGAAGTTTACAGGAGAAAAAATAAAATCAAAATCAAATTTTCAAATAACCACTGACTC AGAGAATGGACCCCAGAAACCCCAGTCCCTCTTGGGGTAATATTTAGGGTGGGTCACTAT AAACAGAGCGGTAAGGCCTGCGGGTGAAAGTGGAGACATCAGACCTTTGGAGGGGCTGGG CTGACCTTCCCCCAAAAAGGAGGGACCCTCTTCGGAGACCCCAGCACACTCGGCTTCTGC CAGGAGGCCAGTGGAGTGGTTTGGACTGTCACCATTAGACCCCGGTGGGGCCCCTTTCTC CTCATCAGGAGCCCAAGGCCTGGCTCCTCTTTCATCCTTGGTAAAGAGCTCTGGGGGGTT TCCCCAGAGGAGCCTGTCCCTCTGCCCCAAATCCTATCATGCTCCCTTATGACCTTCTTT CCAGACCCCCTGAGTGCCGATCCCACCTGTGAAAGGGGAGGAGCAGATCTGGGGAAGGGA TATGCCCAGAGGAAATCAACAAGACCAAAGAGACGTCAGAGTCCTGATGGCCAAAATCAG ACACCAGCTTTCCTGAGAAGGCAGAAGAGAGAGCCCCATAAAAGCAGTGGGGGCTCAGAA GGTTCAGTGGGTTCACAGGGGAGCAAGGCTCCTGAGGGCTACTCAGACAGAAGCACCCCC CAAAAATACTTCCCCTTTTCCTCCCCGGAAACAGACAGATAAGGTTCAAAATTTAGGCCC CAAAGGGGGCACACCCTTCAACCAATTCTATGAAAAACTTGTTGGCCCGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002859 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002859.1, NP_002850.1 |
| RefSeq Size | 3595 bp |
| RefSeq ORF | 1674 bp |
| Locus ID | 5829 |
| UniProt ID | P49023 |
| Domains | LIM, Paxillin |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, VEGF signaling pathway |
| Gene Summary | This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011] Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1 (also known as isoform alpha). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213811 | PXN (Myc-DDK-tagged)-Human paxillin (PXN), transcript variant 2 |
CNY 6,224.00 |
|
| RC213811L1 | Lenti ORF clone of Human paxillin (PXN), transcript variant 2, Myc-DDK-tagged |
CNY 8,624.00 |
|
| RC213811L2 | Lenti ORF clone of Human paxillin (PXN), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC213811L3 | Lenti ORF clone of Human paxillin (PXN), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213811L4 | Lenti ORF clone of Human paxillin (PXN), transcript variant 2, mGFP tagged |
CNY 8,624.00 |
|
| RG213811 | PXN (tGFP-tagged) - Human paxillin (PXN), transcript variant 2 |
CNY 7,824.00 |
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