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Factor H (CFH) (NM_001014975) Human Untagged Clone
CAT＃: SC301971
CFH (untagged)-Human complement factor H (CFH), transcript variant 2
CNY 5,488.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001014975 edited
GGACGTTGTGAACAGAGTTAGCTGGTAAATGTCCTCTTAAAAGATCCAAAAAATGAGACT TCTAGCAAAGATTATTTGCCTTATGTTATGGGCTATTTGTGTAGCAGAAGATTGCAATGA ACTTCCTCCAAGAAGAAATACAGAAATTCTGACAGGTTCCTGGTCTGACCAAACATATCC AGAAGGCACCCAGGCTATCTATAAATGCCGCCCTGGATATAGATCTCTTGGAAATATAAT AATGGTATGCAGGAAGGGAGAATGGGTTGCTCTTAATCCATTAAGGAAATGTCAGAAAAG GCCCTGTGGACATCCTGGAGATACTCCTTTTGGTACTTTTACCCTTACAGGAGGAAATGT GTTTGAATATGGTGTAAAAGCTGTGTATACATGTAATGAGGGGTATCAATTGCTAGGTGA GATTAATTACCGTGAATGTGACACAGATGGATGGACCAATGATATTCCTATATGTGAAGT TGTGAAGTGTTTACCAGTGACAGCACCAGAGAATGGAAAAATTGTCAGTAGTGCAATGGA ACCAGATCGGGAATACCATTTTGGACAAGCAGTACGGTTTGTATGTAACTCAGGCTACAA GATTGAAGGAGATGAAGAAATGCATTGTTCAGACGATGGTTTTTGGAGTAAAGAGAAACC AAAGTGTGTGGAAATTTCATGCAAATCCCCAGATGTTATAAATGGATCTCCTATATCTCA GAAGATTATTTATAAGGAGAATGAACGATTTCAATATAAATGTAACATGGGTTATGAATA CAGTGAAAGAGGAGATGCTGTATGCACTGAATCTGGATGGCGTCCGTTGCCTTCATGTGA AGAAAAATCATGTGATAATCCTTATATTCCAAATGGTGACTACTCACCTTTAAGGATTAA ACACAGAACTGGAGATGAAATCACGTACCAGTGTAGAAATGGTTTTTATCCTGCAACCCG GGGAAATACAGCCAAATGCACAAGTACTGGCTGGATACCTGCTCCGAGATGTACCTTGAA ACCTTGTGATTATCCAGACATTAAACATGGAGGTCTATATCATGAGAATATGCGTAGACC ATACTTTCCAGTAGCTGTAGGAAAATATTACTCCTATTACTGTGATGAACATTTTGAGAC TCCGTCAGGAAGTTACTGGGATCACATTCATTGCACACAAGATGGATGGTCGCCAGCAGT ACCATGCCTCAGAAAATGTTATTTTCCTTATTTGGAAAATGGATATAATCAAAATTATGG AAGAAAGTTTGTACAGGGTAAATCTATAGACGTTGCCTGCCATCCTGGCTACGCTCTTCC AAAAGCGCAGACCACAGTTACATGTATGGAGAATGGCTGGTCTCCTACTCCCAGATGCAT CCGTGTCAGCTTTACCCTCTGA >OriGene 5' read for NM_001014975 unedited
GGGGAGTTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGGA CGTTGTGAACAGAGTTAGCTGGTAAATGTCCTCTTAAAAAATCCAAAAAATGAGACTTCT AGCAAAGATTATTTGCCTTATGTTATGGGCTATTTGTGTAGCAGAAGATTGCAATGAACT TCCTCCAAGAAGAAATACAGAAATTCTGACAGGTTCCTGGTCTGACCAAACATATCCAGA AGGCACCCAGGCTATCTATAAATGCCGCCCTGGATATAGATCTCTTGGAAATATAATAAT GGTATGCAGGAAGGGAGAATGGGTTGCTCTTAATCCATTAAGGAAATGTCAGAAAAGGCC CTGTGGACATCCTGGAGATACTCCTTTTGGTACTTTTACCCTTACAGGAGGAAATGTGTT TGAATATGGTGTAAAAGCTGTGTATACATGTAATGAGGGGTATCAATTGCTAGGTGAGAT TAATTACCGTGAATGTGACACAGATGGATGGACCAATGATATTCCTATATGTGAAGTTGT GAAGTGTTTACCAGTGACAGCACCAGAGAATGGAAAAATTGTCAGTAGTGCAATGGAACC AGATCGGGAATACCATTTTGGACAAGCAGTACGGTTTGTATGTAACTCAGGCTACAAGAT TGAAGGAGATGAAGAAATGCATTGTTCAGACGATGGTTTNTTGGAGTAAAGAGAAACCAA AGTGTGTGGAAATTTCATGCAAATCCCCAGATGTTATAAATGGATCTCCTATATCTCAGA AGATTATTTATAAGGAGAATGAACGATTTCAATATAAATGTAACATGGGTTATGAATACA GTGAAAGAAGAGATGCTGTATGCACTGAATCGGGATGGCGTNCGTTGCCTT >OriGene 3' read for NM_001014975 unedited
NNNCCATTGGNGAATGGCACTTNCCAGGNCCAGNANGAGCACTGGGGNAGGGTCACAGGG NTGCCACCCGGGATCTGTTCAGGAACAGCTATGACCGCGGCCGCAATCTAGATCAGAGGG TAAAGCTGACACGGATGCATCTGGGAGTAGGAGACCAGCCATTCTCCATACATGTAACTG TGGTCTGCGCTTTTGGAAGAGCGTAGCCAGGATGGCAGGCAACGTCTATAGATTTACCCT GTACAAACTTTCTTCCATAATTTTGATTATATCCATTTTCCAAATAAGGAAAATAACATT TTCTGAGGCATGGTACTGCTGGCGACCATCCATCTTGTGTGCAATGAATGTGATCCCAGT AACTTCCTGACGGAGTCTCAAAATGTTCATCACAGTAATAGGAGTAATATTTTCCTACAG CTACTGGAAAGTATGGTCTACGCATATTCTCATGATATAGACCTCCATGTTTAATGTCTG GATAATCACAAGGTTTCAAGGTACATCTCGGAGCAGGTATCCAGCCAGTACTTGTGCATT TGGCTGTATTTCCCCGGGTTGCAGGATAAAAACCATTTCTACACTGGTACGTGATTTCAT CTCCAGTTCTGTGTTTAATCCTTAAAGGTGAGTAGTCACCATTTGGAATATAAGGATTAT CACATGATTTTTCTTCACATGAAGGCAACGGACGCCATCCAGATTCAGTGCATACAGCAT CTCCTCTTTCACTGTATTCATAACCCATGTTACATTTATATTGAAATCGTTCATTCTCCT TATAAATAATCTTCTGAGATATAGGAGATCCATTTATAACATCTGGGGGATTTGCATGAA ATTTCCACCACTTTGGTTTCTCTTTACTCCAAAACCATCGTCTGAACATGCATTTCTTCT C |
| Restriction Sites | Please inquire |
| ACCN | NM_001014975 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | There are 2 nucleotide differences between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 2 amino acids. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001014975.1, NP_001014975.1 |
| RefSeq Size | 1702 bp |
| RefSeq ORF | 1350 bp |
| Locus ID | 3075 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| Gene Summary | This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (2) utilizes an alternate terminal exon which results in an early stop codon. The resulting protein (isoform b, also known as the 'factor H-like 1' or 'FHL-1' isoform) has a distinct C-terminus and is shorter than isoform a. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220772 | CFH (Myc-DDK-tagged)-Human complement factor H (CFH), transcript variant 2 |
CNY 5,488.00 |
|
| RC220772L1 | Lenti ORF clone of Human complement factor H (CFH), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC220772L2 | Lenti ORF clone of Human complement factor H (CFH), transcript variant 2, mGFP tagged |
CNY 7,888.00 |
|
| RC220772L3 | Lenti ORF clone of Human complement factor H (CFH), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC220772L4 | Lenti ORF clone of Human complement factor H (CFH), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG220772 | CFH (tGFP-tagged) - Human complement factor H (CFH), transcript variant 2 |
CNY 7,088.00 |
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