Human ADCY6 activation kit by CRISPRa
CAT#: GA100074
ADCY6 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 6
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ADCY6 |
Locus ID | 112 |
Kit Components | GA100074G1, ADCY6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100074G2, ADCY6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100074G3, ADCY6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_015270, NM_020983 |
Synonyms | AC6; LCCS8 |
Summary | This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN209021 | ADCY6 - human gene knockout kit via CRISPR, HDR mediated |
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KN209021BN | ADCY6 - human gene knockout kit via CRISPR, HDR mediated |
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KN209021LP | ADCY6 - human gene knockout kit via CRISPR, HDR mediated |
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KN209021RB | ADCY6 - human gene knockout kit via CRISPR, HDR mediated |
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KN409021 | ADCY6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |