Human ADCY6 activation kit by CRISPRa

CAT#: GA100074

ADCY6 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 6



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-ADCY6 Antibody
    • 100 ul

CNY 5,250.00


ADCY6 (Myc-DDK-tagged)-Human adenylate cyclase 6 (ADCY6), transcript variant 2
    • 10 ug

CNY 7,768.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ADCY6
Locus ID 112
Kit Components

GA100074G1, ADCY6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100074G2, ADCY6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100074G3, ADCY6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_015270, NM_020983
Synonyms AC6; LCCS8
Summary This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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