Human SETD2 activation kit by CRISPRa

CAT#: GA109212

SETD2 CRISPRa kit - CRISPR gene activation of human SET domain containing 2, histone lysine methyltransferase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SETD2 mouse monoclonal antibody, clone OTI1E1 (formerly 1E1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


SETD2 (Myc-DDK-tagged)-Human SET domain containing 2 (SETD2)
    • 10 ug

CNY 16,928.00


SETD2 mouse monoclonal antibody, clone OTI1E1 (formerly 1E1)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SETD2
Locus ID 29072
Kit Components

GA109212G1, SETD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109212G2, SETD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109212G3, SETD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_012271, NM_014159, NM_001349370, NR_146158
Synonyms FLJ16420; FLJ22472; FLJ45883; HIF1; KIAA1732
Summary Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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