IVD (NM_002225) Human Mass Spec Standard

CAT#: PH301077

IVD MS Standard C13 and N15-labeled recombinant protein (NP_002216)



  View other "IVD" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of isovaleryl Coenzyme A dehydrogenase (IVD), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 100 ug

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Specifications

Product Data
Description IVD MS Standard C13 and N15-labeled recombinant protein (NP_002216)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201077
Predicted MW 46.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002216
RefSeq Size 4673
RefSeq ORF 1269
Synonyms ACAD2; IVDH
Locus ID 3712
Cytogenetics 15q15.1
Summary Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Valine, leucine and isoleucine degradation
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