RFC2 (NM_002914) Human Mass Spec Standard

CAT#: PH301138

RFC2 MS Standard C13 and N15-labeled recombinant protein (NP_002905)



  View other "RFC2" proteins (6)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description RFC2 MS Standard C13 and N15-labeled recombinant protein (NP_002905)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201138
Predicted MW 35.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002905
RefSeq Size 1657
RefSeq ORF 960
Synonyms RFC40
Locus ID 5982
Cytogenetics 7q11.23
Summary This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways DNA replication, Mismatch repair, Nucleotide excision repair
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