HERPUD1 (NM_001010990) Human Mass Spec Standard

CAT#: PH317811

HERPUD1 MS Standard C13 and N15-labeled recombinant protein (NP_001010990)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description HERPUD1 MS Standard C13 and N15-labeled recombinant protein (NP_001010990)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217811
Predicted MW 40.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001010990
RefSeq Size 2123
RefSeq ORF 1098
Synonyms HERP; Mif1; SUP
Locus ID 9709
Cytogenetics 16q13
Summary The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
Protein Families Druggable Genome
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