PF4V1 (NM_002620) Human Mass Spec Standard

Specifications

Product Data
Description	PF4V1 MS Standard C13 and N15-labeled recombinant protein (NP_002611)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC220116
Predicted MW	11.6 kDa
Protein Sequence	Sequence Link (showhide) >RC220116 protein sequence Red=Cloning site Green=Tags(s) MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHC PTAQLIATLKNGRKICLDLQALLYKKIIKEHLES TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002611
RefSeq Size	741
RefSeq ORF	312
Synonyms	CXCL4L1; CXCL4V1; PF4-ALT; PF4A; SCYB4V1
Locus ID	5197
Cytogenetics	4q13.3
Summary	The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients. [provided by RefSeq, Nov 2015]
Protein Families	Secreted Protein
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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