Cofilin 2 (CFL2) (NM_138638) Human Mass Spec Standard

CAT#: PH322215

CFL2 MS Standard C13 and N15-labeled recombinant protein (NP_619579)



  View other "Cofilin 2" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CFL2 MS Standard C13 and N15-labeled recombinant protein (NP_619579)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222215
Predicted MW 18.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_619579
RefSeq Size 3267
RefSeq ORF 498
Synonyms NEM7
Locus ID 1073
Cytogenetics 14q13.1
Summary This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Protein Families Druggable Genome
Protein Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton
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