PR3 (PRTN3) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ala26-Arg249
Tag	C-6His
Buffer	Supplied as a 0.2 um filtered solution of 10mM TrisHCl, 150mM NaCl, 10% Glycerol, pH8.0
Note	Recombinant Human Proteinase 3 is produced by our Mammalian expression system and the target gene encoding Ala26-Arg249 is expressed with a 6His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	5657
UniProt ID	P24158
Summary	Myeloblastin, also known as Human Proteinase 3 is a member of the peptidase S1 family. This protein is expressed by both monocytes and neutrophils, the neutrophils secretes, isolates in azurophilic granules, or expresses Myeloblastin on the cell's surface. When the Myeloblastin is secreted, it activates the kinin pathway and when isolated it aids in digestion of phagocytosed material.

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