CTLA4 Human Recombinant Protein
CAT#: TP727743
Recombinant Human Cytotoxic T-lymphocyte Protein 4 (C-Fc-Avi)
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CNY 1,150.00
货期*
2周
规格
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经常一起买 (1)
CTLA4 mouse monoclonal antibody,clone OTI1G10
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Lys36-Asp161
|
Tag | C-Fc&AVI |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Note | Biotinylated Recombinant Human Cytotoxic T-lymphocyte Protein 4 is produced by our Mammalian expression system and the target gene encoding Lys36-Asp161 is expressed with a Fc, Avi tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 1493 |
UniProt ID | P16410 |
Summary | Cytotoxic T-lymphocyte protein 4, is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4. |
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