CD82 Human Recombinant Protein
CNY 2,920.00
货期*
2周
规格
Product images
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Gly103-Gln225
|
Tag | N-Fc |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
Note | Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3732 |
UniProt ID | P27701 |
Summary | CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer. |
Documents
FAQs |
SDS |
Customer
Reviews
Loading...